Eridanus, the river:

Eridanus is one of the longest and largest constellations in the sky. The constellation represents nearly every major river known to humankind. To the Babylonians it was the Euphrates, to the Egyptians, the Nile. It has also been the Rhine, the Ebro, the Huang He, and the Rhone. Eridanus begins next to the bright star Rigel, which represents the foot of Orion. It then meanders its way through the sky. Eridanus originally ended with the star Acamar, which is the last bright star visible to people living in northern latitudes. As sailors began to travel to the Southern Hemisphere, the constellation was continued to the star Achernar.